Is your staff overwhelmed by appointment, refill, and billing calls while patients struggle to reach care teams through slow, phone-based communication? Investing in a good patient portal software can help care teams address these issues.

Finding the right patient portal software can be cumbersome for some. It is possible to get lost in the sea of options, and we understand your frustration. 

To help you make the right software selection, we have spent hundreds of hours evaluating different EMR/EHRs with patient portal availability. Our research combines hands-on product analysis with insights from clinicians and care managers. 

The software added to our list are analyzed based on scheduling, messaging, record access, and security parameters – features that are vital for the smooth delivery of patient-centered care.

By comparing top options, you can quickly identify solutions that reduce administrative burdens, increase patient satisfaction, and support care coordination.

Best Patient Portal Software Comparison

Software

Rating

Trial Info

Starting Price

Best For

Key Features

Epic

(Editor’s Choice)

4/5

Read Reviews

No free trial

View Demo

Custom pricing

Get A Custom Quote

Practices of all sizes

  • Capacity Command Center
  • Online Scheduling
  • Virtual Visits
  • Remote Consultation
  • Real-time Data Access

athenahealth

4/5

Read Reviews

No free trial

View Demo

Custom pricing

Get A Custom Quote

Practices of all sizes

  • Appointment Reminders
  • Secure Messaging
  • Virtual Consultations
  • Speech-to-text Dictation

NextGen Healthcare

4/5

Read Reviews

No free trial

View Demo

Custom pricing

Get A Custom Quote

Smaller Practices

  • Bills Management
  • Automated Messaging
  • Patient Surveys
  • Prescription Refill Requests

eClinicalWorks (healow)

4/5

Read Reviews

No free trial

View Demo

$449/provider/month

Get A Custom Quote

Practices of all sizes, including independent practices

  • Medical Billing
  • Real-time Access To Medical Records
  • Appointment Scheduling
  • Telehealth

SimplePractice

4/5

Read Reviews

30-day free trial

View Demo

$49/month

Get A Custom Quote

Solo and group practices

  • Secure Messaging
  • Integrated Billing
  • Appointment Management
  • Documentation History Panel

Tebra

3/5

Read Reviews

No free trial

View Demo

Custom pricing

Get A Custom Quote

Independent practices

  • Automated Reminders
  • Payment Portal
  • Unified View Of Patient Health
  • Digital Intake Forms
  • Lab And Test Results

SPRY

N/A

No free trial

View Demo

Custom pricing

Get A Custom Quote

Practices of all sizes

  • Appointment Scheduling 
  • Automated Reminders 
  • Benefits Integration 
  • Analytics And Reporting 

DrChrono

4/5

Read Reviews

30-day free trial

View Demo

Custom pricing

Get A Custom Quote

Practices of all sizes

  • Lab Integration
  • Speech-To-Text
  • Integrated Telehealth
  • Virtual Appointments

Healthie

N/A

 

14-day free trial

View Demo

$19/month

Get A Custom Quote

Solo or small practices

  • Appointment Management
  • Integrated Telehealth
  • Medical Billing

1. Epic - Editor’s Choice

Epic is an enterprise Electronic Health Record (EHR) that comes with an integrated patient portal, MyChart. Its scalability and ability to support patient access across large, multi-entity healthcare organizations are second to none. The portal enables secure messaging, appointment management, and access to clinical records within a tightly integrated Epic ecosystem. This solves the long-standing problem of fragmented data and patient-provider communication lapses.

Pros

Cons

Equips users with various shortcuts to accomplish a task easily

The clean interface helps navigate the complete medical history of patients

Enables easy sharing of patient data across various facilities and systems

The system may seem overwhelming in the beginning due to many features

Frequent updates may disrupt the workflow

Best For

The patient portal offered by Epic software is suitable for practices of all sizes.

Key Features

  • Capacity Command Center
  • Online Scheduling
  • Virtual Visits
  • Remote Consultations
  • Real-time Data Access

Pricing

Epic follows a subscription-based model, and pricing is customized for healthcare organizations. Practices can benefit from the ‘patient portal’ features that are part of its broader EHR ecosystem.

View detailed pricing.

Why We Like It

Epic made the list for its support for patient portal workflows at enterprise scale without fragmentation. Patient data is standardized across departments, and access controls are tightly managed. The portal fits health systems that require consistent patient engagement, strong governance, and reliable coordination across complex care environments.

User Ratings

Rated 4/5 based on multiple user reviews. Users value Epic for its comprehensive, centralized patient record management, though some report that routine workflows require excessive clicking and navigation.

2. athenahealth

athenahealth provides a cloud-based EHR with an integrated patient portal for ambulatory care practices. It offers patient access tools for digital intake, secure messaging, appointment management, and billing transparency, all within a fully hosted platform.

Pros

Cons

Comprehensive reports to track practice performance

Ease of accessing medical history and patients' health records

Practitioners can coordinate care with other providers

Integrated medical billing operations that reduce administrative burdens

The patient portal may occasionally slowdown when dealing with large workloads

Customizing some advanced features can prove complex for new users

Best For

athenahealth's patient portal is suitable for practices of all sizes.

Key Features

  • Appointment Reminders
  • Secure Messaging
  • Virtual Consultations
  • Speech-to-text Dictation

Pricing

athenahealth follows a collection-based approach. The patient portal is part of its EMR, available at a custom price.

Why We Like It

What stands out about athenahealth is how the patient portal integrates patient access to administrative and clinical workflows. This means that digital intake, messaging, and billing visibility are handled in one place. This helps outpatient practices reduce manual work while maintaining consistent patient communication across visits.

User Ratings

Rated 4/5 based on multiple user reviews. Users value athenahealth for its automation and connectivity across clinical and billing workflows, though some of the users mention inconsistent responsiveness from customer support.

3. NextGen Healthcare

NextGen Healthcare offers an EHR with a patient portal designed for ambulatory and specialty practices. It provides configurable patient access features, scheduling capabilities, and support for structured data exchange between patients and care teams.

Pros

Cons

The system offers intuitive navigation across practice management and EHR modules

Seamless onboarding and robust customization support clinical service expansion

Allows patients to access health records, medications, and lab results

Interface appears outdated and lacks a user-friendly layout

System updates and hosting reliability can disrupt operations

Best For

Ideal for smaller practices, NextGen is suitable for behavioral health, orthopedics, and multi-specialty clinics.

Key Features

  • Appointment Scheduling
  • Bills Management
  • Automated Messaging
  • Patient Surveys
  • Prescription Refill Requests

Pricing

Nextgen follows a subscription-based model. Pricing is customized and depends on the selected modules.

Why We Like It

NextGen stands out for its patient portal, which combines configurability with specialty-oriented workflows. The portal supports engagement across the full care cycle, from pre-visit intake to follow-ups. It fits practices that need patient access tools tailored to specialty workflows rather than a generic portal experience.

User Ratings

Rated 4/5 based on multiple user reviews. Users praise NextGen Healthcare EHR for its user-friendly interface and streamlined workflows, though some find the reporting tools confusing and challenging to navigate.

4. eClinicalWorks (healow)

eClinicalWorks features ‘healow’ patient portal as part of its EHR ecosystem. It facilitates mobile and web-based access to health records, appointments, and secure communication - designed to support patient engagement beyond in-person visits.

Pros

Cons

Helps physicians in managing patient accounts

Providers can request prescription refills using an integrated system

Review patient histories, diagnostic tests and lab results with different views

Customer support can be streamlined to offer solutions quicker

Patient engagement tools might slow down due to large workloads, according to some eClinicalWorks reviews

Best For

Ideal for practices of all sizes.

Key Features

  • Medical Billing
  • Real-time Access To Medical Records
  • Appointment Scheduling
  • Telehealth

Pricing

eClinicalWorks’s patient portal is part of its extensive EHR bundle. Following are two subscription tiers offered by the vendor:

  • EHR Only Plan - $449/provider/month
  • EHR with Practice Management - $599/provider/month

Disclaimer: The pricing is subject to change.

Why We Like It

healow is recognized for its patient-facing accessibility and mobile-first approach. Patients can manage appointments, view records, and communicate through a single interface. This makes it a practical option for practices focused on improving portal adoption and ongoing patient participation.

User Ratings

Rated 4/5 based on multiple user reviews. Users appreciate eClinicalWorks for its all-in-one scheduling, billing, and documentation capabilities, though many find routine tasks inefficient and the interface clunky to navigate.

5. SimplePractice

SimplePractice is a practice management and EHR platform with a built-in patient portal. The portal supports online scheduling, intake forms, and secure messaging, commonly used in behavioral health and wellness practices.

Pros

Cons

Provides a user-friendly interface for ease of use

Integrates seamlessly across multiple devices and locations

Provides comprehensive client portal features for convenience

Offers comprehensive billing and invoicing features for financial management

Extensive documentation and note-taking capabilities enable thorough record-keeping

Support response time may vary during peak hours

Limited customization options for certain functionalities, according to a SimplePractice review

May require additional training for optimal utilization

Best For

Well-suited for solo and group practices in the mental and wellness industry.

Key Features

  • Secure Messaging
  • Integrated Billing
  • Appointment Management
  • Documentation History Panel
  • Telehealth

Pricing

SimplePractice’s patient portal is a part of all its core plans. The vendor offers the following three subscription plans:

  • Starter – $49/month
  • Essential – $79/month
  • Plus – $99/month

Disclaimer: The pricing is subject to change.

Why We Like It

SimplePractice earns its place in the list of top patient portal software by streamlining communication between staff and patients. It works well for smaller practices that want patient engagement tools without added operational complexity.

User Ratings

Rated 4/5 based on multiple user reviews. Users praise SimplePractice for its organized, intuitive interface and consolidated workflow, though some report occasional telehealth connectivity and performance issues.

6. Tebra

Tebra offers an EHR with an integrated patient portal built for independent medical practices. It is included for its patient access capabilities that support scheduling, digital intake, and secure communication as part of daily practice operations.

Pros

Cons

Helps acquire patients with online presence

Real-time tracking helps maintain practice well-being

Can be integrated with your current EHR

Appointment reminders and secure messaging help reduce no-shows

Process automation simplifies complex billing workflows

The software pricing is not publicly available

The support staff's response time could be improved

Best For

Tebra is well-suited for independent practices in cardiology, dermatology, and internal medicine specialties.

Key Features

  • Automated Reminders
  • Payment Portal
  • Unified View Of Patient Health
  • Digital Intake Forms
  • Lab And Test Results

Pricing

Tebra offers custom pricing based on the needs of practices.

Why We Like It

Tebra is notable for positioning the patient portal as part of practice operations, not just patient communication. It connects patient activity directly to the front-office workflows. This makes it suitable for independent practices focused on efficiency and growth.

User Ratings

Rated 3/5 based on multiple user reviews. Users praise Tebra for its intuitive, user-friendly design that simplifies daily practice tasks, though some note occasional issues with ICD code lookups during documentation.

7. SPRY

SPRY provides a practice management platform with a patient portal tailored for therapy and rehabilitation practices. It is appreciated for its structured intake processes, scheduling tools, and patient communication features that support extended care plans.

Pros

Cons

User-friendly interface for easy navigation

Tailored workflows for physical therapy clinics

AI-powered features help automate daily practice tasks

Offers comprehensive analytics for data-driven decisions

Integrated digital intake enhances patient satisfaction and experience

Customization complexity for a few advanced features

The initial implementation process may require additional training for staff

Best For

SPRY EMR is geared towards physical therapy practices. Practices of all sizes can benefit from the features of its patient portal.

Key Features

  • Appointment Scheduling
  • Automated Reminders
  • Benefits Integration
  • Analytics And Reporting

Pricing

SPRY EMR follows a subscription-based model and offers the following standard pricing options:

EHR and Practice Management

  • Essentials – Custom pricing
  • Plus – Custom pricing
  • RCM and Billing
  • Billing – 4-6% of collections

Disclaimer: The pricing is subject to change.

Why We Like It

SPRY offers support for extended care journeys, which makes it different from generic patient portals. It enables structured intake and ongoing communication throughout treatment plans. It is well-suited for therapy and rehabilitation practices where patient engagement continues well beyond the first visit.

User Ratings

Users praise SPRY for its intuitive documentation and efficient workflow that saves time, though some mention occasional glitches.

8. DrChrono

DrChrono is a cloud-based EHR with a patient portal designed to support patient engagement features like scheduling, intake, and secure communication. It offers mobile accessibility and flexibility in managing patient interactions across clinical settings.

Pros

Cons

Offers the ability to create and modify clinical templates

The mobile-friendly design allows healthcare professionals to access patient records quite easily

Efficient EHR capabilities, including e-prescribing, lab integration, etc.

The patient portal and online check-in features help increase patient engagement

The performance can be hindered by unstable internet connectivity

The initial setup can be time-consuming, as per some DrChrono reviews

Best For

DrChrono features workflows that are suitable for practices of all sizes.

Key Features

  • Lab Integration 
  • Speech-To-Text 
  • Integrated Telehealth 
  • Virtual Appointments 
  • E-prescriptions 
  • Claims Management 

Pricing

DrChrono offers flexible pricing plans. They offer customized pricing plans as per the practice’s needs. The following are some of the pricing plans offered by DrChrono:

  • Essentials - EHR & Practice Management
  • Essentials Plus - EHR, ePrescribe & Practice Management
  • Advanced - EHR, Practice Management & Billing
  • Advanced Plus - EHR, ePrescribe, Practice Management & Billing
  • Elite - EHR, ePrescribe, Practice Management & Billing Services

Disclaimer: The pricing is subject to change.

Why We Like It

DrChrono’s patient portal is valued for its flexibility and mobile access. Intake forms, messaging, and scheduling can be managed without slowing clinical workflows. This makes it a strong option for practices that operate in fast-paced or mobile environments.

User Ratings

Rated 4/5 based on multiple user reviews. Users value DrChrono for its integrated clinical workflow and mobile support, though some find the interface and documentation workflows inefficient and clunky.

9. Healthie

Healthie is a care management platform with a patient portal built to support ongoing engagement. It is included for its tools that enable messaging, document sharing, and appointment coordination in longitudinal care models.

Pros

Cons

User-friendly system simplifies patient communication

Streamlines practice management with easy scheduling and billing

User-friendly platform backed by excellent customer support

Could benefit from more feature customization options

Reporting flexibility might be enhanced for diverse practices

Best For

Ideal for solo and small practices seeking a reliable patient portal.

Key Features

  • Appointment Management
  • Integrated Telehealth
  • Medical Billing

Pricing

Patient Portal is a part of Healthie’s EMR ecosystem. The vendor follows a subscription-based model, and the following are the subscription tiers offered by Healthie:

  • Core – $19/month
  • Essentials – $49/month
  • Plus – $129/month
  • Group – $149/month

Disclaimer: The pricing is subject to change.

Why We Like It

Healthie is designed around continuous patient interaction rather than episodic visits. The portal supports regular messaging, document sharing, and appointment coordination. It fits practices that manage longitudinal care and require consistent patient touchpoints.

User Ratings

Users praise Healthie for its all‑in‑one practice management features and intuitive workflow, though some find that form customization and integrations could be more flexible.

Key Buying Advice

Choosing the right patient portal software directly impacts patient engagement, operational efficiency, and care coordination. Focus on solutions that match your practice size, specialty, and workflows. Prioritize security, interoperability, and usability for both patients and staff. Involving clinicians, IT, and administrative teams early ensures smooth adoption and long-term value from the portal.

How To Choose The Best Patient Portal Software

When evaluating patient portal software, consider features that support both clinical and administrative needs. Look for secure messaging, appointment management, online forms, telehealth capabilities, and access to clinical records. Integration with your existing EHR and practice management system is essential.

Assess usability for patients and staff, scalability for future growth, reporting and analytics capabilities, and vendor support. Engage key stakeholders to ensure the platform aligns with workflows, patient engagement goals, and compliance requirements.

What Not To Overlook

  • HIPAA and data security compliance
  • EHR and practice management integration
  • Mobile access and patient usability
  • Telehealth and digital care features
  • Workflow alignment for clinicians and staff
  • Scalability for future growth
  • Vendor support and training quality