Running a healthcare practice is becoming more expensive every year. Recent data from 2025 shows that 90% of medical groups reported higher year-to-date operating expenses compared to 2024, with an average increase of 11.1%. This steady rise in costs means small to mid-sized practices must be even more careful when choosing tools like electronic health record (EHR) systems, which can directly impact efficiency, care quality, and overall financial performance.
CureMD and Practice Fusion are two popular EHR options that cater to a range of growing practices. Both offer an advanced suite of tools to streamline clinical and administrative workflows, but they differ in features, pricing, and overall usability.
In this CureMD vs Practice Fusion comparison, we will break down the key differences between the two platforms to help you decide which one is the better fit for your practice.
Head-On Comparison
CureMD is a cloud-based EHR platform designed to support a wide range of medical specialties with integrated practice management and billing services. It offers customizable workflows, specialty-specific templates, and a user-friendly interface accessible on iPad and iPhone. The system includes tools for scheduling, eligibility checks, medical billing, and MIPS/MACRA reporting to help practices stay compliant and financially efficient. CureMD was also ranked the top EMR by Black Book in 2025 and offers award-winning support to streamline care delivery and improve the patient experience.
Practice Fusion is a cloud-based EHR and billing platform designed to help independent medical practices across more than 30 specialties operate more efficiently. It offers tools for charting, e-prescribing, patient communication, and billing within a user-friendly interface. The platform is built with input from healthcare providers to reduce administrative burden and improve patient care. Trusted by over 112,000 medical professionals, Practice Fusion supports a wide range of practice needs with an intuitive, human-centered design.
CureMD Vs Practice Fusion: At A Glance
Feature
CureMD
Practice Fusion
E-Prescribing
✓
✓
AI Capabilities
✓
✓
Telemedicine
✓
✓
Patient Portal
✓
✓
Scheduling
✓
✓
Electronic Labs
✓
✓
Billing Services
✓
✓
Interoperability
✓
✓
Pros And Cons
Pros
Customizable user interface options
Stores long-term lab reports
Multiple calendar view options
Simplifies follow-up coordination
Well-organized charting workflows
Cons
Difficult vaccine input process
Slow and inefficient claim follow-ups
Delayed customer support responses
Pros
Customizable medication order sets
Works well across most specialties
Macros simplify the documentation process
Responsive and user-friendly design
Great accessibility across devices
Cons
Difficult to delete appointments
Doesn’t track metrics over visits
No built-in faxing feature
Side-By-Side Comparison
Both CureMD and Practice Fusion are widely used EHR platforms designed to support small to mid-sized healthcare practices. This side-by-side comparison highlights their core features, helping you decide which system better fits your clinical workflows and operational needs.
E-Prescribing
CureMD: Offers an award-winning e-prescribing solution that connects prescribers with over 40,000 pharmacies nationwide. It supports both mail-order and retail pharmacies and includes advanced safety features such as drug-drug, drug-allergy, and drug-diagnosis interaction checks. The platform also provides age- and weight-based dose adjustments, real-time eligibility and formulary checks, and controlled substance e-prescribing (EPCS). Moreover, CureMD integrates complete medication history and enables precision medicine by tailoring prescriptions to individual patient profiles.
Practice Fusion: Also offers a comprehensive e-prescribing software solution with certified EPCS support, automatic medication reconciliation, allergy alerts, and drug interaction checks. The system streamlines workflow with quick order submissions, two-click refill processing, and prior authorization management, all from within the EHR. Providers can also use patient-focused tools like ‘eCoupons’ to lower costs, verify orders through e-prescribing reports, and help prevent fraud by securely transmitting prescription data from the EHR.
Winner: CureMD edges ahead with its more extensive safety features, precision medicine capabilities, and broader pharmacy connectivity.
Billing Services
CureMD: Provides a highly advanced and full-service medical billing solution designed to reduce administrative burdens and improve cash flow. It combines nearly 30 years of billing experience with AI-driven claims scrubbing, a constantly updated rules engine, and end-to-end revenue cycle management support. Key tools include a 'KPI Dashboard' for real-time performance tracking, 'E-super Bill' for coding accuracy, and automated eligibility checks at patient check-in. CureMD also offers extensive payer follow-up, denial management, secondary billing, and patient statement services.
Practice Fusion: Also delivers a strong set of integrated billing services designed to support independent practices. It offers claims scrubbing, same-day submissions, insurance payment posting, denial management, and payer compliance tools. The platform includes a 'Payer Enrollment Dashboard', electronic and paper statements, and a dedicated billing team with over 30 years of experience across 45 specialties. Practice Fusion focuses on clean claim submission, operational efficiency, and transparent reporting to help practices meet their financial goals.
Winner: CureMD stands out with its AI tools and real-time performance insights, which make it a more comprehensive solution for practices seeking greater financial visibility.
EHR And Charting
CureMD: Provides a customizable EHR system that blends AI-powered charting, specialty-specific templates, and integrated diagnostics into a unified experience. Providers can streamline workflows using its iOS-based mobile app, ‘Avalon’, and customize charting workflows with rebuilt specialty templates. With customizable workflows and automation tools, CureMD helps reduce documentation time while ensuring seamless integration with lab, imaging, and billing systems.
Practice Fusion: Offers a fully cloud-based EHR with intuitive charting and real-time access across devices. It provides a library of customizable templates, lab and imaging order management, flowsheets for tracking patient health, and built-in reporting tools like ‘Patient List Reports’ and ‘Diagnosis Registries’. The platform also supports automatic updates, drug interaction alerts, and shareable structured results to improve clinical accuracy and collaboration, especially for smaller practices that require flexible, low-maintenance tools.
Winner: Practice Fusion edges ahead due to its fully cloud-based design, broader device compatibility, and built-in reporting tools that simplify day-to-day EHR use.
Patient Engagement
CureMD: Offers a comprehensive patient engagement solution through its ‘Life Extension and Advancement Platform’ (LEAP). Patients can check in digitally, review post-visit summaries, access lab results, and receive intelligent medication reminders. This patient portal also includes real-time vitals tracking through wearable integrations, secure messaging with care teams, family member access, and AI-driven alerts for gaps in care. Additional features like ‘Conversational AI’, smart refill tools, personalized education content, and integrated billing further enhance the patient experience.
Practice Fusion: Supports patient engagement through its cloud-based patient portal software solution. Patients can view their health records in real time, communicate securely with providers, book appointments, request refills, and receive appointment reminders via text, email, or phone. Providers can also send ‘eCoupons’, distribute educational content, and flag at-risk patients. The portal is optimized for mobile use and helps reduce administrative workload with online intake forms and HIPAA-compliant messaging tools.
Winner: CureMD stands out with a more advanced and personalized patient engagement platform that offers AI-powered alerts, wearable integration, and smart communication tools.
Practice Management
CureMD: Offers an all-in-one practice management solution that ties together scheduling, billing, reporting, inventory, and workflow automation. Its scheduling tool supports multiple providers and locations with features like recurring appointments, real-time eligibility checks, and copay collection prompts. The platform also includes a built-in clearinghouse, KPI dashboards, audit trails, denial management, and inventory tracking, making it well-suited for both small and multi-location practices seeking operational control and financial oversight.
Practice Fusion: Focuses on simplifying front-desk tasks for small practices. Its ‘Online Check-In’ tool lets patients complete customizable intake forms before visits, saving time and reducing manual entry. The system also allows users to manage appointment requests directly from the EHR, with patient demographic and insurance information flowing automatically into the encounter note.
Winner: CureMD wins with its advanced scheduling, billing, and workflow tools that support more complex practice management needs.
Pricing Comparison
CureMD follows a personalized pricing model tailored to the specific needs of each practice. It offers four core modules, which include ‘Practice Management’, ‘Electronic Health Records’, ‘Billing Services’ (starting as low as 3% of collections), and an ‘All-in-One' package that combines PM and EHR. Costs vary based on practice size, specialty, and required features, allowing organizations to only pay for what they need.
Practice Fusion offers transparent, fixed pricing starting at $199/provider/month, billed annually. The plan includes three signing staff licenses and unlimited non-signing staff licenses, with essential EHR tools such as charting, e-prescribing, patient portal access, and appointment scheduling. This model suits small practices looking for an affordable, predictable monthly cost.
Disclaimer: The pricing is subject to change.
Overall, CureMD is ideal for practices seeking scalable, specialized pricing, while Practice Fusion works well for providers who prefer a transparent, fixed monthly fee.
What Users Have To Say?
We analyzed real user reviews for both CureMD and Practice Fusion to understand what providers like about each platform and where they believe improvements are needed. Here’s a summary of their experiences:
CureMD earns praise for its customizable user interface, which allows providers to visualize data and reports in a way that suits their workflow. Users appreciate the seamless integration across billing, patient data, and lab reports, along with the ease of using the platform on mobile devices like iPads. The patient portal is also frequently highlighted as intuitive and easy to navigate.
However, some users find CureMD’s browser limitations frustrating, as the system performs best only in Internet Explorer. Others report that the billing department can be slow to respond; template flexibility is limited, and certain features like color-coded appointments and report customization are missing.
Practice Fusion is widely appreciated for its simplicity and affordability. Users value the ease of use across staff roles, especially the quick onboarding and organized interface. Features like macros (dot phrases) make documentation faster, and its broad lab and imaging integration is seen as a major plus for smaller practices.
On the downside, some users are disappointed by the limited functionality of its online check-in tools and report issues with real-time insurance authorization not working as expected. Additionally, the lack of a fully integrated practice management system is seen as a drawback for practices seeking an all-in-one solution.
Final Verdict: CureMD Vs Practice Fusion
Both CureMD and Practice Fusion offer valuable tools to help healthcare providers digitize workflows, improve patient care, and stay organized. However, they serve different practice types and priorities.
CureMD is ideal for small to mid-sized practices that need an all-in-one, scalable solution with integrated EHR, billing, and practice management features. Practice Fusion, on the other hand, is a better fit for solo providers and small private practices looking for a simple, affordable EHR that covers the essentials without added complexity.
