Find the Best Best Oncology EMR/EHRs

Oncologists today face ‘time toxicity’ where the growing complexity of treatments and rising patient volumes stretch clinical teams thin and compromise care delivery. Modern oncology electronic medical record (EMR) systems help ease this burden. These tools bring patient data into one place, support accurate treatment planning, and cut down repetitive administrative work.

However, finding an EMR that covers the full needs of an oncology practice isn’t simple. The specialty is complex, with multimodal treatments, multiple specialists, and detailed patient records. Managing all of this efficiently requires a system that can keep everything connected and accessible.

This guide helps oncology practices choose the right EMR. We analyzed industry reports and spoke with oncologists and clinic staff to deliver practical, evidence-based guidance on features, benefits, and selection criteria.

Oncology EMR software is specifically designed for oncologists to document treatments and follow-ups for patients undergoing cancer care. It has become a fulcrum of cancer care for patients and oncologists alike, enhancing clinical decision-making, strategic workflows, and the management of treatments. This includes the administration and ordering of chemotherapy drugs, hematology, cancer-specific templates and workflows, as well as features for cancer registries, reporting, and clinical trials.

Oncology medical software also helps prevent procedural errors by ensuring accurate documentation, correct drug dosages, and timely treatment plan adjustments.  It also stores results from complex procedures, such as PET scans, mammograms, and CT scans, so clinicians and patients can access critical data for effective care.

Overall, clinicians can coordinate care and manage progress through a centralized platform to ensure patients receive safe and consistent care throughout their journey.

When exploring oncology EMR systems, it is important to understand what features matter most. We analyzed thousands of reviews on Software Finder to determine the core features of these systems and what makes them most valuable for oncology practices:

How We Evaluated Oncology EMR Systems

We at Software Finder gathered insights from oncologists, infusion nurses, and practice administrators who use these EMR systems in real-world oncology settings. Our evaluation is based on a multi-step methodology designed to objectively assess each platform’s performance. This includes:

• Data Analysis: Our process started by reviewing industry reports from the American Society of Clinical Oncology (ASCO) and KLAS Research to define core requirements for oncology EMR systems. We then analyzed insights gathered from in-depth interviews and verified third-party reviews to evaluate each system’s strengths, limitations, and overall suitability for oncology workflow
• Workflow Assessment: Each EMR was examined for how well it supported critical oncology workflows, including chemotherapy ordering and CPOE safety checks, infusion documentation, genomic data management, and long-term patient follow-up
• Quantitative Evaluation: We quantified the frequency and impact of recurring patterns in the data, such as error rates, workflow bottlenecks, and adoption levels. This allowed us to prioritize features and identify consistent strengths and challenges across vendors
• Final Synthesis: All findings were compiled into pros and cons lists for each vendor to give oncology practices an evidence-based guide for selecting EMR systems that fit their workflow needs

Epic

Pros:

• 65% of users praise ‘Epic Beacon’ for streamlining complex oncology workflows and automating critical tasks
• The platform is also highly appreciated for its customization and scalability by over 40% of users

“Epic’s customization options are waves ahead of any other EMR. You can truly configure it to fit our practice needs. It makes complex workflows feel simple and ensures our team can work exactly the way we want.”

Cons:

• Some users, however, mention that implementation is demanding and costly as well as requires significant effort from clinicians and IT

"Using the comprehensive Beacon treatment plans is a heavy lift. Success depends on strong operations and IT leadership."

Cerner (Now Oracle Health)

Pros:

• About 60% users highlight Cerner’s versatility and scalability, noting that it can be implemented across a range of healthcare settings
• 52% of users also praise its customizable templates, dashboards, and workflow tools, which help support care planning for complex oncology treatments

“The templates for common notes work really well and fit our oncology workflows perfectly. They save time and help reduce errors.”

Cons:

• Some users report that the user interface can feel unintuitive at first, requiring extra clicks and time to navigate, particularly during initial adoption

“There are too many clicks required to complete simple tasks. For example, reviewing family history or medications takes three clicks when one would be enough.”

CureMD

Pros:

• Approximately 75% of users praise CureMD for its user-friendly and intuitive interface

"The software is very easy to navigate and has proven to be a streamlined EMR.”

• User feedback also highlights its responsive customer support and smooth implementation

“Their customer support is truly amazing, I never have to wait too long on the phone, and they get started on the issue almost immediately. The implementation process was pretty quick. Our staff adapted smoothly, and we were able to start using the system effectively from day one.”

Cons:

• On the downside, some users report delays and issues with billing and claims processing

“During claim scrubbing, we occasionally faced time-related issues that need improvement.”

ARIA Oncology Information System

Pros:

• 30% of users commend ARIA’s ability to support both medical and radiation oncology in a single platform

"It is very impressive how ARIA Oncology software system supports both our medical and radiation departments. Having both areas on one platform makes coordinating patient care much smoother and reduces errors caused by switching between systems."

About 80% users appreciate the system for its user-friendly interface and thorough training

"I really love how much free time I have now because work does not take me as long. The training was detailed and clear, so our team was able to start using the system effectively from day one without major hiccups."

Cons:

• However, performance and stability issues were mentioned by roughly 30% of users

“Certain processes, like imaging, can be slow or unresponsive, which interrupts workflow and requires extra effort to keep everything on track.”

OncoEMR By Flatiron Health

Pros:

• Many users appreciate Flatiron’s proactive support and vendor responsiveness, with about 25% noting that the team actively helps with integrations and keeps the system updated

"Flatiron is always very good at providing proactive service. They give us advanced notice of updates and help with our integration goals."

• 49% of reviewers also find the system user-friendly and intuitive

"OncoEMR is a very user-friendly system. It is very easy to teach new employees about it, and the layout helps us move from one screen to another quickly."

Cons:

• Limited customization frustrates about 15% of users, particularly those managing unique workflows or multi-site setups

"I don't like the fact that they can't make changes as per our work practice unless several sites want to make a change. It can be frustrating when you need something adjusted quickly. This limitation makes it difficult to tailor the system to our specific needs."

Here's a list of the benefits oncology clinics can expect when using an EMR designed specifically for their specialty and workflows:

Automated Workflows

An oncology EMR can improve several key aspects of your practice. It saves time, which means you and your staff can focus on more tasks and direct patient engagement each day. It ensures greater accuracy by reducing human error, supporting patient safety. Additionally, it makes treatment strategies safer by automatically adjusting and tailoring protocols to patients’ specific needs, including preemptive considerations for potential complications—such as compensating for renal adversities when devising radiation oncology plans.

Improved Chemotherapy Management

Modern oncology EMR systems can draw patient information from an entire database and more (referential information from credible internet sources) to create customized treatment plans for every sign or symptom scenario. A systematic review of 14 studies found that implementing Computerized Provider Order Entry (CPOE) within oncology EMRs significantly reduced medication errors across all phases of chemotherapy.

Enhanced Data Capture And Analysis

Oncology EHR software constantly analyzes data, patient and clinician feedback, and treatment responses, making these processes intuitive and easy to manage. Both oncologists and their staff can efficiently document their treatment actions to fully capture all the details of the patient's journey. The EHR also supports long-term data monitoring and capture, as cancer treatment paths are rarely short-term like those for some other acute conditions.

Data Sharing And Interoperability

Oncology EMR systems make it easy to share data with experts and ensure they have all the information they need to make the best decisions. Not only this, but these tools also support research efforts to fight against cancer. A 2024 study by the Association of Cancer Care Centers (ACCC) and TriHealth found that integrating discrete genomic data directly into an EMR system increased clinician adoption of genomic tests. This shows how seamless data integration can improve both clinical decision-making and research potential.

Easy Post-Treatment Care

Taking care of cancer patients doesn't end when they leave the hospital. An EMR software tailored for oncology practices also supports care teams in providing high-quality care post-treatment. Clinicians can easily create a follow-up plan with a good oncology EHR suite and share it with others. Whether it's rehabilitation or follow-up procedures at different facilities, the system enables seamless collaboration and keeps everyone in the loop.

Here are some key factors you should consider to ensure the EMR software aligns with the long-term goals of your oncology practice:

The cost of oncology EMR software can vary widely depending on factors such as practice size, deployment type, number of users, and the level of customization needed.

Specialized oncology features like chemotherapy management, cancer staging, and clinical trial support can also affect pricing. Here’s what practices can realistically expect:

Estimated Costs

• Small- To Medium-Sized Practices: For advanced systems like Epic, first-year costs including setup, training, and initial data migration typically range from $30,000 to $70,000/physician
• Ongoing Cloud-Based Subscription Fees: Monthly fees for cloud-based oncology EMRs can range from $600 to $1,300/user/provider, depending on system capabilities and included features
• Other Costs To Consider: Charges for system integrations, optional modules, and ongoing vendor support or maintenance may add to the total investment

Disclaimer: The estimates have been sourced from third-party sites and are subject to change.

Return On Investment (ROI)

While upfront and ongoing costs for oncology EMRs can be significant, providers often see substantial long-term value. The system can streamline workflows, reduce administrative burden, and improve charge capture, which can help increase reimbursements. Over time, these operational, financial, and clinical benefits typically outweigh the initial investment.

The oncology EMR software market is evolving rapidly in 2025 – largely driven by the rising global cancer burden, longer patient survivorship, and advances in personalized treatment approaches. Nearly 20 million cancer cases were diagnosed worldwide in 2022, with an age-standardized rate of 196.9 per 100,000 people. In the U.S., over 2 million new cancer cases are projected for 2024, along with approximately 611,720 cancer-related deaths.

The growing number of cancer patients, along with increasingly complex treatment plans, highlights the urgent need for oncology-specific EMRs. These systems help practices manage large volumes of patient data, streamline chemotherapy orders, and reduce dosing errors – all crucial for improving efficiency and patient care.

Moreover, advanced technologies like Artificial Intelligence (AI), machine learning, and genomic data analytics are transforming oncology EMRs. They provide predictive insights, enable personalized treatment plans, and offer real-time guidance for targeted therapies.

For example, the TriHealth Precision Medicine Institute in Cincinnati, Ohio, integrated genetic information directly into its Epic EHR system. This integration improved clinical adoption and made operations more efficient. It shows how oncology EMRs can centralize complex data and support precision medicine.

Interoperability is also becoming a key trend in oncology EMRs, as practices demand seamless data exchange across labs, imaging systems, and genomic platforms. Initiatives like Minimal Common Oncology Data Elements (mCODE) and FHIR are driving standardization to enable more integrated and efficient cancer care.

Oncology practitioners report that specialized EMRs improve efficiency and patient safety by centralizing data and automating workflows. Users praise intuitive interfaces, customizable templates, and decision support tools that reduce documentation time and promote evidence-based care. Some note limited flexibility or occasional slow performance that can disrupt workflows. Overall, many practitioners find oncology-specific EMRs to be valuable tools in modern cancer care.